Arimidex Anastrozole/Treatment of Advanced Metastatic Breast Cancer in Postmenopausal Women
Arimidex Anastrozole/Treatment of Advanced Metastatic Breast Cancer in Postmenopausal Women
Anastrozole is a non-steroidal aromatase inhibitor and a third-generation aromatase inhibitor. It is clinically used to treat advanced metastatic breast cancer in postmenopausal women. Anastrozole can lower estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Anastrozole is usually given to women whose cancer is not well controlled with tamoxifen (Nolvadex, Soltamox).
Anastrozole
Generic name: Anastrozole
Product name: Arimidex
Full Name: Arimidex, anastrozol, 阿那曲唑，瑞宁得，anastrozole
Indications of Anastrozole
1. It is suitable for the treatment of advanced breast cancer in postmenopausal women. For patients with negative estrogen receptors, if they have a positive clinical response to tamoxifen, this product can be considered.
2. It is suitable for adjuvant therapy of hormone receptor positive early breast cancer in postmenopausal women.
3. It is suitable for the adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women who have received 2 to 3 years of adjuvant tamoxifen therapy.
Dosage of Anastrozole
1. Once a day, 1 mg each time.
2. It can be taken in the morning or evening, before or after meals, and swallow the whole medicine.
Side Effects of Anastrozole
Serious Adverse Reactions:
1. Skin reactions, such as skin lesions, ulcers or blisters.
2. An allergic reaction to swelling of the face, lips, tongue, or throat (which may cause difficulty swallowing or breathing).
3. Changes in liver function blood tests, including liver inflammation.Symptoms may include general malaise, presence or absence of jaundice, liver pain, or liver swelling.
Common adverse reactions in women (≥10%):
1. Hot flashes, fatigue, arthritis, pain
2. Arthralgia, high blood pressure, depression, nausea and vomiting
3. Rash, osteoporosis, fracture, back pain
4. Headache, bone pain, peripheral edema, aggravated cough
5. Dyspnea, pharyngitis and lymphedema, insomnia
Adverse reactions (>0.1%) of discontinuation of treatment in the trial:
hot flashes
Taboo
1. Hypersensitivity to anastrozole or any component of the preparation.
2. Pregnant women are prohibited.
3. Premenopausal women.
4. Patients with severe renal impairment (creatinine clearance less than 20ml/min).
Storage
Store at controlled room temperature, 20-25°C (68-77°F)
Keep away from light, sealed
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