Jan 7, 2023 Viewed: 47

Nolvadex Tamoxifen/Treating Advanced Breast and Ovarian Cancer


Nolvadex Tamoxifen/Treating Advanced Breast and Ovarian Cancer

Introduction of Nolvadex Tamoxifen

Nolvadex Tamoxifen, an organic compound with the molecular formula C26H29NO, is clinically used to treat advanced breast cancer and ovarian cancer. In the clinical treatment of breast cancer, the effective rate is generally 30%, and the curative effect is better in patients with estrogen receptor positive (49%), and the curative effect in negative patients is poor (7%). Both premenopausal and postmenopausal patients can be used, and postmenopausal and people over 60 years of age are more effective than premenopausal and younger patients. From the point of view of lesion site, skin, lymph nodes and soft tissue have good curative effect, while bone and visceral metastasis have poor effect. On October 27, 2017, the list of carcinogens released by the International Agency for Research on Cancer of the World Health Organization was initially compiled for reference, and tamoxifen was included in the list of category 1 carcinogens.

Indications for Tamoxifen

1. Postoperative adjuvant therapy for breast cancer, especially for postmenopausal patients over 60 years old, has a better effect on estrogen receptor positive patients.

2. Advanced breast cancer, or recurrence after treatment. It has good curative effect on skin, lymph node and soft tissue metastasis.

3. Endometrial cancer.

Contraindications to Tamoxifen

1. Pregnant women and those with thromboembolic diseases.

2. Patients with a history of deep vein thrombosis.

3. Those with a history of pulmonary embolism.

Precautions

1. It should be used with caution in patients with visual impairment and liver and kidney insufficiency.

2. For patients who take this product for a long time and are at risk of thromboembolism, the blood picture should be checked regularly during treatment. If there is bone metastases, blood calcium needs to be checked regularly in the initial stage of treatment. During the long-term treatment with this product for more than 2 years, the liver function should be tested regularly.

3. When abnormal vaginal bleeding occurs, seek medical attention immediately and conduct a comprehensive examination. The drug should be discontinued in case of profuse vaginal bleeding.

4. Patients treated with this product have an increased risk of endometrial cancer, so careful gynecological examinations should be carried out.

5. Sudden ovarian functional cysts, menorrhagia and irregular uterine bleeding may occur when using this product. Therefore, if this drug must be used before menopause, antigonadotropic drugs should be taken at the same time.

Adverse Reactions

1. Gastrointestinal reactions: loss of appetite, nausea, vomiting, diarrhea.

2. Secondary anti-estrogen effects: facial flushing, genital itching, menstrual disorders, amenorrhea, increased leucorrhea, vaginal bleeding, etc.

3. Neuropsychiatric symptoms: headache, dizziness, depression, etc.

4. Long-term application of large doses can cause visual impairment, such as cataracts.

5. Bone marrow suppression: a small number of patients may have transient leukopenia and thrombocytopenia.

6. Others: skin rash, hair loss, weight gain, abnormal liver function, etc.

Dosage

1. Breast cancer: It has a better effect on breast cancer patients with estrogen receptor positive. Oral administration of 10-20 mg each time, 2 times a day.

2. Endometrial cancer: This product can increase the level of progesterone receptor. Those with low progesterone receptor levels can first use this product to increase the receptor level, and then treat with progesterone, or apply both at the same time to improve the curative effect. The general dose is 10-20 mg orally each time, 2 times a day.

 

Drug Evaluation

The effective rate of this product in the clinical treatment of breast cancer is generally about 30%. Patients with positive estrogen receptors have a better curative effect, while those with negative estrogen receptors have a poorer curative effect. Both premenopausal and postmenopausal patients can be used, and postmenopausal medication is more effective than premenopausal and younger patients. From the point of view of lesion site, skin, lymph nodes and soft tissue have good curative effect, while bone and visceral metastasis have poor effect. The efficacy of this product in treating ovarian cancer is superior to other estrogen preparations, while the side effects are significantly lower.

We can do all kinds of products for muscle bodybuilding,such as sarms, testosterrone,whey protein powder, viagra and so on. Pls contact us directly,let's talk it off line.
   We can do OEM as your inquiry(Ingredients, dosage, packaging, logo)

Lauren Qi

WhatsApp: +8615350592113

Wickr Me: unifychem

E-mail:lauren@buy-growthhormone.com

 

Related Search:

Nolvadex

nolvadex tamoxifen for sale

Tamoxifen

nolvadex tamoxifen 10 mg

nolvadex bodybuilding

nolvadex是什么药

nolvadex testosterone

nolvadex steroid





More blogs    






CONTACT
US