Orlistat/Obesity Medicine
Orlistat/Obesity Medicine
Orlistat is an obesity treatment drug that does not act on the central nervous system. It only acts on the gastrointestinal tract. By inhibiting the lipase in the gastrointestinal tract, it prevents the hydrolysis of triacylglycerol into free fatty acids and monoacylglycerides, reduces the absorption of fat (triacylglycerol) in the intestinal mucosa, and promotes the excretion of fat from the body. . Lipase is an enzyme necessary for the decomposition of fat in the gastrointestinal tract. This product can be combined with the serine residue of gastric and pancreatic lipase to inactivate the lipase, so that it cannot decompose the fat in food into free fatty acids, and inhibit the formation of fat. Utilization and absorption, in addition, this product can still reduce the risk factors related to obesity.
Combined with a minimally low-calorie diet, it is suitable for the long-term treatment of obese and overweight patients, including those who have developed risk factors related to obesity. It has the effect of long-term weight control (weight loss, weight maintenance and prevention of rebound). May reduce obesity-related risk factors and incidence of other obesity-related diseases, including hypercholesterolemia, type 2 diabetes.
Dosage
Adults: The recommended dose is one 120mg capsule taken with or within one hour after a meal. A dose may be omitted if a meal is missed or if the food does not contain fat. The therapeutic effect (including weight control and improvement of risk factors) of long-term Xenical administration can be sustained. The patient's diet should be nutritionally balanced, slightly low in calories, about 30% of the calories come from fat, and the food should be rich in fruits and vegetables. The intake of fat, carbohydrates and protein should be distributed among three meals a day. There is no evidence that more than three times a day / each 120mg can enhance the efficacy. No dosage adjustment is required for the elderly.
Adverse Reactions
It mainly causes gastrointestinal adverse reactions, which are related to the pharmacological effect of the drug to prevent the absorption of ingested fat.
1. Common adverse reactions are: oily spots, increased gastrointestinal exhaust, stool urgency, fatty (oily) stool, steatorrhea, increased stool frequency and fecal incontinence.
2. Acute gastrointestinal reactions that usually occur more often in patients taking Xenical include: abdominal pain/abdominal discomfort, flatulence, watery stools, soft stools, rectal pain/rectal discomfort, tooth discomfort, gum discomfort .
3. Other rare adverse events observed include: upper respiratory tract infection, lower respiratory tract infection, influenza, headache, menstrual disorders, anxiety, fatigue, urinary tract infection.
4. There are occasional reports of allergy to this product. The main clinical manifestations are pruritus, rash, urticaria, angioedema, and allergy.
Taboo
Chronic malabsorption syndrome, cholestasis and patients allergic to orlistat or any of the ingredients in the drug preparation are contraindicated.
Precautions
After no more than two years of orlistat treatment, the vitamin A, D, E, K and β-carotene levels of most patients were still within the normal range. In order to ensure that there are enough nutrients, you can consider supplementing with multivitamins. Patients should be educated to follow dietary instructions (see Dosage and Administration). When Xenical is combined with a high-fat diet (for example, in a day of 2000 calories, more than 30% of the calories come from more than 67 grams of fat supply), the possibility of gastrointestinal events (see adverse reactions) will increase. Daily fat intake should be distributed among the three main meals. The likelihood of gastrointestinal reactions increases when Xenical is taken with a meal that is high in fat. In patients with type 2 diabetes, Xenical resulted in weight loss, often accompanied by improved blood sugar control.
We are a strong manufacturer of pharmaceutical raw materials, pharmaceutical intermediates and reagents, mainly engaged in steroids, PEPTIDE, MT2, bodybuilding, slimming, etc., with stable product performance, advanced technology, fast delivery, and safe and convenient logistics. And continuous scientific research and innovation, can meet more needs of customers. We will be your best partner, and our mutually beneficial cooperation will allow each other to gain more market and profits.
Lauren
Hebei Uni-President Biopharmaceutical Co., Ltd.
WhatsApp: +8615350592113
Wickr Me: unifychem
E-mail:lauren@buy-growthhormone.com
Related Search:
orlistat中文
orlistat减肥
orlistat是什么
Orlistat side effects
Xenical
How orlistat was discovered
Orlistat HEXAL
Orlistat history